Needle Bonding

A main field of application for adhesives in medical systems is needle bonding and syringe assembly – the bonding of stainless steel needles or cannulas into glass or plastic syringes. The needles’ required high withdrawal forces are achieved through precision manufacture (needle position, adhesive dosing and reliable adhesive curing), choice of hub (material and design) and, in particular, the right adhesive system.

Already the hub material used affects the choice of adhesive, since not all adhesives adhere well to all plastics. Many adhesives are UV-curing, which requires the use of transparent and UV-permeable materials. For materials that block UV light, such as polycarbonates, long-wave LED curing is recommended. All needle bonding adhesives listed in the table below can be LED-cured.

The hub design also plays an important role for the assembly of syringes: it determines whether a mobile adhesive that flows into the needle hub through capillary action or a highly viscous adhesive capable of filling large gaps is used. In some cases the needle shaft must be designed with grooves to provide an additional key for the adhesive.

Hoenle offers various adhesives that are suitable for bonding stainless steel needles into glass syringes and stainless steel cannulas into syringes made from plastics such as PC, PVC, PP or ABS. All adhesives recommended for needle bonding are solvent-free and certified USP Class IV and/or ISO 10993 for use in medical equipment. In addition, high needle extraction forces were measured with all needle bonding adhesives even after several sterilization cycles. Electron-beam sterilization has even been shown to improve the adhesion of some adhesives of the Vitralit® series.

All adhesives are also available in fluorescent versions, which allows a fast and efficient quality control during production.

The table below lists a selection of needle bonding adhesives from Hoenle. Further products and custom solutions for needle assembly are available on request. To download the technical datasheets (TDS) please click on the adhesive name.

Adhesive Application Areas Viscosity [mPas] Base Curing * Special Properties
  • needle bonding
  • bonding glass apparatus
600-900 acrylate UV VIS secondary heat cure
  • non-yellowing
  • excellent flow properties
  • certified to USP Class VI and ISO 10933-5 standards
  • needle bonding
  • bonding glass apparatus
3,000-6,000 acrylate UV VIS secondary heat cure
  • non-yellowing
  • excellent gap-filling
  • certified to USP Class VI standards
  • shear thinning
  • Needle bonding,
  • Bonding enclosures,
  • Bonding of plastics
  • Bonding Medical Devices
70 (Rheometer, 25°C) acrylate UV VIS
  • Excellent adhesion to glass, plastics and metals;
  • biocompatible: certified to ISO 10993-5 standards;
  • Capillary flow, resistant to sterilization;
  • CMR-free, IBOA-free
  • Needle bonding,
  • Bonding dialysis filters,
  • Bonding of plastics
  • Bonding medical devices
2,200 (Rheometer, 25°C, 10s^-1) acrylate UV VIS
  • High viscosity/stable, CMR-free, IBOA-free
  • excellent adhesion to glass, plastics and metals;
  • biocompatible: certified to USP Class VI and ISO 10993/-4/-5 standards
  • Plastic bonding, glass bonding
  • Suitable for large area bonding
  • Suitable for applications with small gaps
40-70 (Newtonian liquid, Rheometer, 25 °C) acrylate UV VIS
  • Fluorescing orange
  • Capillary flowing
  • Resistant to moisture and alcohol
  • Biocompatible, certified according to USP Class VI and ISO 10993-5/10
  • Resistant to sterilization
  • Needle bonding
  • Plastic bonding
170 (Rheometer, 25°C) acrylate UV VIS
  • Certified to ISO 10993-5 standards, CMR-free,
  • impact resistant, very fast curing
  • very high adhesion to plastics
  • needle bonding
  • plastic bonding
6,000-10,000 (Rheometer, 25°C, 10s^-1) epoxy thermal
  • Black color
  • excellent flow properties
  • filling material for frame&fill applications
  • high resistance to heat and chemicals
  • certified to ISO 10993-5 standards

*UV = 320 – 390 nm          VIS = 405 nm

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